Position Details
Position Information
| Recruitment/Posting Title |
Post Doctoral Associate (Ebright) |
| Department |
Waksman Inst of Microbiology |
| Salary |
Annual Salary |
| Benefits |
Rutgers offers a comprehensive benefit program to eligible employees. For details, please go to
http://uhr.rutgers.edu/benefits/benefits-overview. |
| Posting Summary |
Conducts research on
RNA polymerase structure and function and on small-molecule inhibitors of
RNA polymerase. Uses cryo-ET, cryo-EM, and X-ray crystallography to define structures and structural transitions of transcription complexes and transcription-translation complexes and to identify and characterize small-molecule inhibitors of transcription. Prepares and assays proteins and nuceleic acids. Prepares and assays ribosomes. Prepares text, tables, and figures for patent applications publications. Presents results at scientific meetings.
Performs professional level experiments and research using various techniques. Carries out routine and non-routine work with review of work outputs by supervisor. Documents work performed and maintains a notebook and database. Communicates effectively with supervisor. Uses and helps maintain highly specialized equipment, in addition to maintaining and keeping the workplace and laboratory organized in a clean and safe manner in accordance with established procedures. Trains and leads research staff, postdoctoral associates, students, and technicians in laboratory related activities. Performs professional work requiring specialized knowledge and application and use of concepts, theories, terminology, and practices. |
| Position Status |
Full Time |
| Posting Number |
25FA0500 |
| Posting Open Date |
|
| Posting Close Date |
|
Qualifications
| Minimum Education and Experience |
Requires a doctorate in biochemistry, molecular biology, or an allied field.
Requires in-depth understanding and hands-on experience in preparation and analysis of proteins, nucleic acids, and complexes thereof.
Requires in-depth understanding and hands-on experience in molecular cloning, sequencing, and site-directed mutagenesis.
Requires in-depth understanding and hands-on experience in cryo-EM, cryo-ET, and/or X-ray crystallography, including sample preparation, data collection, and data processing.
In-depth understanding and hands-on experience in cryo-EM and/or cryo-ET, including sample preparation, data collection, and data processing, preferred.
Experience in structural and functional analysis of
RNA polymerase and transcription complexes and/or ribosomes and translation complexes preferred.
Effective spoken and written English required.
High level of computer literacy required.
Experience in chromatography (including
FPLC and preferably including
HPLC) and electrophoresis required. Experience in work with chemical hazards and radiological hazards required. Experience in work with biological hazards (biosafety levels 1 and 2) preferred. |
| Certifications/Licenses |
|
| Required Knowledge, Skills, and Abilities |
Above in description |
| Equipment Utilized |
Above in description |
| Physical Demands and Work Environment |
Average to above-average levels of mobility expected for laboratory environment.,
Average to above-average levels of upper-body strength expected for lifting and working with bioreactors, large-volume culture flasks, Dewar flasks, cryo reservoirs, and other heavy items. |
| Overview |
Scope & Impact:
Describe the level of job complexity and scope of influence (university, campus, school, program, project, etc.).
Laboratory.
Does this position have the authority and accountability for policy development, compliance, and/or administration? If yes, provide an explanation.
No.
What is the position's accountability for organizational and/or strategic planning?
None
In addition, describe the complexity of functional areas for which this position is responsible.
Under broad direction from the PI, the position holder will serve as an instructor, monitor, and mentor for students and lower-level employees.. |
| Statement |
Key Duties:
100 %
1. Research transcription-complex and transcription-translation-complex structure and function and on small-molecule inhibitors of
RNA polymerase. Conducts research on transcription-complex and transcription-translation-complex structure and function and on small-molecule inhibitors of
RNA polymerase. Uses cryo-ET, cryo-EM, and X-ray crystallography to define structures and structural transitions of transcription complexes and transcription-translation complexes and to identify and characterize small-molecule inhibitors of transcription. Develops, validates, optimizes, and applies procedures for sample preparation, data collection, and data analysis. Prepares and characterizes ribosomes, proteins, nucleic acids, small-molecules, and complexes thereof. Performs molecular cloning and site-directed mutagenesis. Prepares text, tables, and figures for patent applications and publications. Presents results at scientific meetings.
Expected outcomes:
* Assigned projects completed on time and within budgetary guidelines
* Analyses conducted using standard and specialized methods and in accordance with established procedures
* Detailed documentation of all procedures and results
* Clear communication of all procedures and results
* Work conducted independently (with supervision as necessary) |
Posting Details
| Special Instructions to Applicants |
|
| Quick Link to Posting |
https://jobs.rutgers.edu/postings/249688 |
| Campus |
Rutgers University-New Brunswick |
| Home Location Campus |
Rutgers University - New Brunswick |
| City |
Piscataway |
| State |
NJ |
| Location Details |
Waksman Institute of Microbiology, 190 Frelinghuysen Road, Piscataway |
Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings. Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination. Affirmative Action/Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement |
Rutgers University
May 06, 2025