Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 97 |
Business Account Executive, TTR - San Antonio, TX
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enh...
8h
| Job Type | Full Time |
Associate Director, QuantSci Technical Solutions
Cambridge, Massachusetts
Associate Director, QuantSci Technical Solutions Overview The Associate Director, QuantSci Technical Solutions is responsible for leading and implementing the Quantitative Sciences vision for data and analysis infrastructure platforms and o...
8h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking discovery biology scientist forleading the charge of delivery solutions in priority tissues/cell types with compelling therapeutic targets. The successful candidate will have excellent ...
8h
| Job Type | Full Time |
Senior Director, AI and Analytics
Cambridge, Massachusetts
Overview We are seeking a Senior Director, AI and Analytics with a passion for architecting solutions, building systems, and delivering real business impact through hands-on contribution. As Senior Director, you will own the enterprise AI c...
8h
| Job Type | Full Time |
Senior Director, Product Communications
Cambridge, Massachusetts
Overview Reporting to the Chief Corporate Communications Officer, this role will oversee our product communications function encompassing 4 globally marketed brands, and 3 late-stage product candidates. This role's primary responsibility wi...
8h
| Job Type | Full Time |
Cambridge, Massachusetts
CTMS Administrator Overview The CTMS Administrator is responsible for performing the day-to-day operations and support of the Alnylam Clinical Trial Management System (CTMS) for the execution of clinical trials across the development portfo...
8h
| Job Type | Full Time |
Manager, Site and Monitoring Health Lead
Cambridge, Massachusetts
Overview The Site and Monitoring Health Lead (SMH Lead) will apply knowledge of regulations and GCPs as well as experience in monitoring to safeguard the quality of clinical trial execution at investigator sites and ensure Alnylam's oversig...
1d
| Job Type | Full Time |
Director, Global Investigations and Enterprise Risk Management, Ethics & Compliance
Cambridge, Massachusetts
Overview Reporting to the Head of Global Investigations & Enterprise Risk Management, the Director, Ethics & Compliance, is responsible for managing all aspects of Alnylam's global investigations in all markets, including conducting and rep...
1d
| Job Type | Full Time |
Director, Clinical Research-CNS
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with flexibility and confidence to work across diseases within the neurology therapeutic area. This role includes the opportunity to provide clinical leade...
1d
| Job Type | Full Time |
Senior Manager, GCP Process Excellence
Cambridge, Massachusetts
Overview Reporting to the Associate Director of Standards, Process & Training - Clinical Development, the Sr Manager, GCP Process Managementserves as a process excellence Subject Matter Expert (SME) on process improvement, management and ef...
1d
| Job Type | Full Time |